Objectives: This study analyzed the association with risk drinking behaviors, health promotion factors, and safety awareness levels among college students. Methods: The data was collected from 2,713 college students by the health and safety survey. It examined the association between health-related factors and risk drinking behavior, such as high-risk drinking, monthly binge drinking, and alcohol use disorder, by multiple logistic regression. Results: The factors affecting high-risk drinking, monthly binge drinking, and alcohol use disorder among college students were age, breakfast eating, current smoking, and life safety awareness. Risk drinking behavior was the higher rate in the group between 19~20 years old or the 1st to 2nd grade. Risk drinking behaviors were related to breakfast eating, current smoking, physical activity, and life safety consciousness level. The high rate of monthly binge-drinking rate among female students is a very remarkable result. Conclusion: Health promotion of college students is an essential task as it affects their adaptation to university life and academic achievement. It should establish campus-based university health and safety policies to prevent the risk of drinking.